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产品目录

所在位置:所有产品 > 抗体抗原 > 一抗 > PUMA/BBC3抗体
PUMA/BBC3抗体图片
产品货号:
Z24581
中文名称:
PUMA/BBC3抗体
英文名称:
Anti-PUMA/BBC3 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-PUMA/BBC3 Antibody
指标别名BBC3;JFY 1;JFY1;PUMA
克隆性Polyclonal
检验物种human,mouse,rat
应用范围WB
基因名称BBC3
抗体来源Rabbit
抗体类型IgG
免疫原A synthetic peptide corresponding to a sequence at the C-terminus of human PUMA(145-159aa ADDLNAQYERRRQEE),identical to the related rat and mouse sequences.
实际分子量21KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料The p53 upregulated modulator of apoptosis,or PUMA,is a pro-apoptotic member of the Bcl-2 protein family.The PUMA gene is located at 19q.PUMA transcript is contained within 4 exons,with the presumptive initiation codon in exon 2.The predicted 193-amino acid PUMA protein shares 91% amino acid identity with the murine sequence.Bcl-2 family members can form hetero- or homodimers,and they act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities.The expression of PUMA is regulated by the tumor suppressor p53,and PUMA has been shown to be involved in p53-mediated apoptosis.Additionally,PUMA encodes 2 BH3 domain-containing proteins,PUMA-alpha and PUMA-beta,that are produced through the use of an alternative first exon and are induced in cells following p53 activation.Furthermore,PUMA couples the nuclear and cytoplasmic proapoptotic functions of p53.
Uniprot IDQ9BXH1
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称BCL2 binding component 3
蛋白名全称Bcl-2-binding component 3
推荐稀释比
Western blot(WB) 1:500~2000

相关搜索:PUMA/BBC3抗体PUMA抗体BBC3多抗Anti-PUMA/BBC3 Antibody
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